Kahriq Chatmon8,694 Points
Flickr API Challenge with no jQuery
Steven Parker182,492 Points
It's possible, but AJAX may be the place where jQuery shines brightest. Besides greatly simplifying the request syntax, it performs some functions "under the hood" that might be particularly difficult to replicate such as resolving many CORS security issues.
Masha Blair12,999 Points
You should use Fetch API -- which is a new, native JS API for making AJAX requests instead of vanilla JS. Treehouse has a class for it. It's just as simple as jQuery AJAX.