using (" ") and (' ') on a variation does it make an difference?

Well you see there's really no particular difference between the two. It is most likely depends on what your coding style is example

I use (" ") for strings and I use (' ') for smaller strings or char.

This can also be used to escape some cases. example will be:

"where you want double quotes to appear inside the string (e.g. for html attributes) without having to escape them, or vice versa" -reference to stackoverflow (don't know how to explain this case properly so yeah I need to google it for best possible explanation.)

Ezekiel is right. Most of the time it is preference unless you are trying to write a string that contains quotation marks, then you will need to use both:

var string = '<h1 class="heading">My Site</h1>';